Diagnosis and Managementof Malignant Pleural Effusions

It is a great pleasure to invite you to a Symposiumon Diagnosis and Management of Malignant Pleural Effusions at Zealand University Hospital, Roskilde, Denmark.

Malignant pleural effusions (MPE) are increasingly commondue to improved cancer survival. The annual incidence of MPE averages that of breast cancer or prostate cancer. MPE inflicts a significant symptom burden on the patient, and isusual a marker of poor prognosis. Both cancer-specifictreatment and generic interventions ameliorate this condition.

We will discuss challenges in diagnostic workup as pleuralfluid cytology does not identify all cases of MPE. Surgicalthoracoscopy can be prevented by medical thoracoscopy orby biopsies guided by thoracic ultrasound. The timing ofcancer-specific treatment and definite pleural proceduressuch as pleurodesis and indwelling pleural catheders will bediscussed.

We would like to share with you our thoughts on this disease that crossed the borders between oncology andpulmonology and hope to welcome you at the Symposium.

We look forward to seeing you Friday,15 November, 2019 at Zealand University Hospital, Roskilde.

Uffe Bødtger, Senior Consultant, MD, PhD, associateprofessorDepartment of Medicine, Zealand University Hospital,Roskilde and Næstved hospitals Chairman of the Pleural Interest Group of Danish Society ofRespiratory Medicine.

Paul Frost Clementsen, Senior Consultant, MD, DMSc,associate professorDepartment of Medicine, Zealand University Hospital,Roskilde

Program

9:30 - Registration and coffee

10:00 - Welcome Peder Fabricius & Uffe Bødtger

10:20 - Malignant pleural effusions(MPE): causes, prognosis,morbidity & mortality - Nick Maskell

11:15 Coffee break

11:30 Diagnostic workup Karin Armbruster

11:45 CT and PET-CT - Simon B Reuter

12:15 Thoracic ultrasound Christian B Laursen

12:45 Medical thoracoscopy Paul Frost Clementsen

13:00 Lunch break

13:45 Treatment of patients with MPE - Rahul Bhatnagar

14:30 Oncological treatment orpleurodesis first?- Jens Benn Sørensen

14:45 Trapped lung,septated/loculated MPE - Rahul Bhatnagar

15:00 Coffee break

15:15 Pleural service in UK - Nick Maskell

15:40 Pleural service in Denmark - Henrik Kirstein

15:55 Closing remarks - Uffe Bødtger

Faculty

Nick Maskell is Professor of Respiratory Medicine a tUniversity of Bristol and Consultant Respiratory Physician atNorth Bristol NHS Trust. He is internationally recognized asa key opinion leader in pleural disease and Co-chaired theBritish Thoracic Society guidelines in the management ofmesothelioma in 2018. He was on the writing committeefor the European mesothelioma guidelines due out inSeptember 2019 and the American guidelines on malignantpleural effusions published in 2019. He is also Co-chair ofthe 2020 British Thoracic Society guidelines on pleuraldisease. Professor Maskell’s research interests relate totranslational studies in all aspects of pleural disease and hasauthored of more than 140 scientific papers to date.

Rahul Bhatnagar is a Consultant Respiratory Physician atNorth Bristol NHS Trust and an Honorary Lecturer at theUniversity of Bristol. He has gained a PhD in themanagement of malignant pleural disease and was the trialco-ordinator for the IPC-Plus and TAPPS trials. His otherresearch interests include pleural infection, noveltechnologies, and improving the patient experience. He hasorganised and acted as faculty at numerous British ThoracicSociety and European Respiratory Society events andcourses, and has taught extensively on pleural interventionand thoracic ultrasound.

Karin Armbruster is consultant pulmologist at UniversityHospital Herlev Gentofte (capital region). She is particularlyinterested in investigation and treatment of pleuraldiseases.

Jens Benn Sørensen is a Consultant Oncologist and AssociateProfessor at Dept. of Oncology, Rigshospitalet/CopenhagenUniversity Hospital. His maininterests are treatment of Lung Cancer and MalignantPleural Mesothelioma and he is co-author of the Fast-trackdiagnosis and treatment guidelines (Pakkeforløb)for both Lung Cancer and for Mesothelioma at the Nationalfor both Lung Cancer and for Mesothelioma at the NationalHealth Board. He is National Co-ordinator of the treatmentguidelines for Malignant Pleural Mesothelioma and has acomprehensive scientific publication in these topics.

Christian B Laursen is a consultant pulmonologist andChristian B Laursen is a consultant pulmonologist andassociate professor at the Department of RespiratoryMedicine, Odense University Hospital, Denmark. His clinicalinterests and main research areas are thoracic ultrasoundand ultrasound guided procedures.

Henrik Kirstein is a consultant pulmonologist at AalborgHenrik Kirstein is a consultant pulmonologist at AalborgUniversity Hospital, region of North Jutland. For the past 12years he has had the responsibility for the multidisciplinarywork up for the diagnosis and staging of lung cancer andmalignant pleural mesothelioma. He is particularlyinterested in invasive procedures.

Paul Frost Clementsen is a consultant pulmonologist andPaul Frost Clementsen is a consultant pulmonologist andassociate professor at Zealand University Hospital, Roskilde.He is particularly interested in simulator based training andassessment of competence in endoscopic ultrasonographyand other invasive procedures including MedicalThoracoscopy for the diagnosis and staging of cancer in lungor pleura.

Uffe Bødtger is a consultant pulmonologist and associateUffe Bødtger is a consultant pulmonologist and associateprofessor at the Departments of Respiratory Medicine,Næstved University Hospital, and Zealand UniversityHospital, Roskilde. Denmark. His clinical interest and mainresearch area is diagnosis of suspected cancer in lung orpleura.

Simon Reuter is a medical doctor and PhD. He is interestedSimon Reuter is a medical doctor and PhD. He is interestedin diagnostics and malignancies, with a particular interest inthe tumor microenvironment and biomarkers.

The Symposium is partially sponsored by an unrestrictedThe Symposium is partially sponsored by an unrestrictedgrant from VingMed.